Journal of Veterinary Science & Medical Diagnosis ISSN: 2325-9590

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Case Report, J Vet Sci Med Diagn Vol: 2 Issue: 3

Gonadotropin-Releasing Hormone Immunization to Treat Urethral Sphincter Mechanism Incompetence in a Bitch that Experienced an Adverse Reaction to Phenylpropanolamine

CE Donovan1, A Weston2 and MA Kutzler1*
1Department of Animal and Rangeland Sciences, Oregon State University, Corvallis, OR, USA
2Town and Country Animal Clinic, Corvallis, OR, USA
Corresponding author : Michelle Kutzler
312 Withycombe Hall, Oregon State University, Corvallis OR 97331, USA
E-mail: [email protected]
Received: July 19, 2013 Accepted: September 25, 2013 Published: September 30, 2013
Citation: Donovan CE, Weston A, Kutzler MA (2013) Gonadotropin-Releasing Hormone Immunization to Treat Urethral Sphincter Mechanism Incompetence in a Bitch that Experienced an Adverse Reaction to Phenylpropanolamine. J Vet Sci Med Diagn 2:3. doi:10.4172/2325-9590.1000119

Abstract

Gonadotropin-Releasing Hormone Immunization to Treat Urethral Sphincter Mechanism Incompetence in a Bitch that Experienced an Adverse Reaction to Phenylpropanolamine

A 12 year old spayed female Queensland heeler mix was presented for the evaluation of unconscious urine leakage that occurred when the dog was sleeping. Urinalysis revealed no abnormalities and the dog was diagnosed with urethral sphincter mechanism incompetence. Phenylpropanolamine was prescribed and resolved incontinence but resulted in lethargy, anxiety, and nasal and ocular discharge. Discontinuation of phenylpropanolamine resolved these symptoms, but incontinence recurred. The dog was then treated by immunizing against GnRH.

Keywords: GnRH immunization; Dog; Phenylpropanolamine; Urinary incontinence; Ovariectomy; Ovariohysterectomy

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