International Journal of Ophthalmic PathologyISSN: 2324-8599

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Research Article, Int J Ophthalmic Pathol Vol: 1 Issue: 2

Incidence of Benign and Malignant Eyelid Tumors in Japan

Hiroshi Toshida1*, Naoki Mamada2, Takuro Fujimaki2, Toshinari Funaki2, Nobuyuki Ebihara2, Akira Murakami2 and Shigekuni Okisaka2,3
1Department of Ophthalmology, Juntendo University Shizuoka Hospital, Japan
2Department of Ophthalmology, Juntendo University School of Medicine, Japan
3Laboratory of Ophthalmic Pathology Education, Japan
Corresponding author : Hiroshi Toshida
Department of Ophthalmology, Juntendo University Shizuoka Hospital, 1129 Nagaoka, Izunokuni, Shizuoka 410-2295, Japan
Tel: +81-55-948-3111; Fax: +81-55-948-3351
Received: August 24, 2012 Accepted: September 26, 2012 Published: September 30, 2012
Citation: Toshida H, Mamada N, Fujimaki T, Funaki T, Ebihara N, et al. (2012) Incidence of Benign and Malignant Eyelid Tumors in Japan. Int J Ophthalmic Pathol 1:2. doi:10.4172/2324-8599.1000102


Purpose: To report incidence of eyelid tumors and tumor-like lesions that were examined histopathologically.

Methods: We reviewed retrospectively 118 eyelid tumors that were examined histopathologically at the Department of Ophthalmology of Juntendo University School of Medicine over a 15-year period. The incidence of each disease and the rate of malignancy were investigated.

Results: The subjects included 47 males and 71 females, with an average age at removal of lesions 47.8 ± 23.7 years old. There were 106 benign tumors (89.8%), with the most common cases being 23 nevi, followed by 18 squamous cell papilloma, 14 seborrheic keratosis and 10 epidermal cysts. Among 12 cases (10.2%) with malignant tumors, the number of males was 4 and females 8. The malignant tumors consisted of basal cell carcinoma (4 cases), malignant lymphoma (3 cases), squamous cell carcinoma and sebaceous carcinoma (2 cases each), and Bowen’s disease (1 case). The average age at removal of the malignant tumors was 53.1 ± 20.7 years old, although the males were significantly younger than the females (33.8 ± 24.0 years old versus 62.8 ± 10.2 years old) (t-test, p<0.05).

Conclusions: Malignant tumors accounted for 10.2%, and the age at removal was younger in male.

Keywords: Tumor; Eyelid tumor; Incidence; Eye; Adnexa

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