Journal of Virology & Antiviral ResearchISSN: 2324-8955

Research Article, J Virol Antivir Res Vol: 3 Issue: 1

Occult Hepatitis B among Patients under Hemodialysis at Mansoura University Hospitals: Prevalence and Risk Factors

Maysaa El Sayed Zaki1, Douaa Rafaat1, Ahmed Eliwa1 and Mostafa Abdelsalam2
1Clinical Pathology Department, Mansoura faculty of Medicine, Egypt
2Internal Medicine Department, Mansoura faculty of Medicine, Egypt
Corresponding author : Maysaa El Sayed Zaki
Mansoura-Rabaea street, Egypt
Email: [email protected]
Received: February 18, 2014 Accepted: April 22, 2014 Published: April 25, 2014
Citation: Zaki MS, Rafaat D, Eliwa A, Abdelsalam M (2014) Occult Hepatitis B among Patients under Hemodialysis at Mansoura University Hospitals: Prevalence and Risk Factors. J Virol Antivir Res 3:1. doi:10.4172/2324-8955.1000118

Abstract

Occult Hepatitis B among Patients under Hemodialysis at Mansoura University Hospitals: Prevalence and Risk Factors

Background: In spite of the progress made in the prevention of transfusion transmitted infections over the last decade, transmission of hepatitis viruses like B and C infection through transfusion of serologically negative blood has been documented among susceptible patients who are under hemodialysis due to end stage renal failure. Aim: The present study was performed to diagnose Occult Hepatitis B among patients under hemodialysis at Mansoura University Hospitals and to determine the risk factors for such infection. Material and method: The study was conducted on 96 patients attending Mansoura University hospitals for hemodialysis with age range from 26 to 65 years. In addition, one hundred sixty seven healthy blood donors were included in the study and considered as a control group. Blood samples were obtained from each subject and subjected to full biochemical analysis for liver function tests and serological markers for hepatitis C IgG (HCV IgG), hepatitis B surface antigen (HBsAg), hepatitis B surface antibody(HBs Ab), hepatitis B core IgG and IgM (HBc IgG & HBc IgM). Furthermore molecular study for hepatitis B viral DNA and its genotypes were performed by multiplex polymerase chain reaction.

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