International Journal of Ophthalmic PathologyISSN: 2324-8599

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Case Report, Int J Ophthalmic Pathol Vol: 4 Issue: 2

A Case of Choroidal Metastasis Determined to be Hepatocellular Carcinoma

Neepa Shah1*, Nicholas Bhojwani2, Adrian Au3, Vivian Lee1,4, Franz Fogt4 and Joan M O’Brien1
1Department of Ophthalmology, Scheie Eye Institute, University of Pennsylvania Health System, Philadelphia, PA, USA
2Department of Radiology, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, OH, USA
3Case Western Reserve University School of Medicine, Cleveland, OH, USA
4Department of Pathology and Laboratory Medicine, Penn Presbyterian Medical Center, University of Pennsylvania Health System, Philadelphia, PA, USA
Corresponding author : Neepa Shah, Scheie Eye Institute, Presbyterian Medical Center 51 N 39th St. Philadelphia PA 19104, USA
Tel: 215-662-8100
Received: June 10, 2015 Accepted: July 07, 2015 Published: July 15, 2015
Citation: Shah N, Bhojwani N, Au A, Lee V, Fogt F, et al. (2015) A Case of Choroidal Metastasis Determined to be Hepatocellular Carcinoma . J Ophthalmic Pathol 4:2. doi:10.4172/2324-8599.1000160


An 80-year-old monocular patient presented with progressively worsening vision in his right eye. He was noted to have choroidal metastasis in this eye and was subsequently admitted for a thorough work-up per oncology to find a primary tumor. After whole body imaging was completed, he was found to have hepatocellular carcinoma proven histopathologically from liver biopsy. He was treated with external beam radiation therapy and his visual acuity and imaging at one-month follow-up showed no improvement. This case highlights the interesting relation between two highly vascular organs – the liver and the choroid - and the diagnostic challenge that exists with choroidal metastases from an unknown primary tumor. It also underscores the need for additional studies to determine whether primary tumor type affects therapeutic management and prognosis.

Keywords: Hepatocellular carcinoma; Uveal metastasis; Choroidal metastasis

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