Journal of Virology & Antiviral ResearchISSN: 2324-8955

Short Communication, J Virol Antivir Res Vol: 6 Issue: 1

Do ABO and Rhesus Blood Groups Affect Susceptibility to, and Prognosis of Ebola Virus Infection?

Brian Conton1,2, Sahr Gevao1,3, Foday Sahr3,4, Osman Kargbo1,5, Philip Kamara5, Abdulai Bah3, Thomas Massaquoi4, Baimba Idriss4, Foday Sesay4, Adeshola Williams6, Samuel Baker5, Sylvester Nicol6, James B Russell3
1Global Emerging Pathogens Treatment Consortium (GET), Ghana
2Physio-Fitness rehabilitation Center, Freetown, Sierra Leone
3College of Medicine and Allied Health Sciences, University of Sierra Leone
434 Military Hospital, Wilberforce, Freetown, Sierra Leone
5National Safe Blood Transfusion Services, Connaught Hospital, Freetow, Sierra Leone
6Davidson Nicol Medical Centre, Freetown, Sierra Leone
Corresponding author : Brian Conton
Physio-Fitness rehabilitation Centre, 36 Kingharman road Freetown, Sierra Leone
Tel: 232 88 626262
E-mail: [email protected]
Received: December 05, 2016 Accepted: December 28, 2016 Published: January 04, 2017
Citation: Conton B, Gevao S, Sahr F, Kargbo O, Philip K, et al. (2017) Do ABO and Rhesus Blood Groups Affect Susceptibility to, and Prognosis of Ebola Virus Infection? J Virol Antivir Res 6:1. doi: 10.4172/2324-8955.1000165

Abstract

In 2014, the largest Ebola outbreak known to man, thundered through West Africa. It infected close to 30,000 people, and killed over 11,000. Yet, though we have known about Ebola for almost forty years, little data is available on survival and infection patterns of this viral hemorrhagic disease. Examining parallels between blood groups and human disease susceptibility is a valid, and increasingly used method of finding such patterns. This study permitted the observation of the different blood groups in Ebola infected patients and survivors. This was compared against the blood group distribution of the general population as well as those within the study, who succumbed to the disease. Blood group A in particular rose to 36.36% of the survivor population in our study, when it only forms 21.1% of the normal population. It formed 9% of the deceased group. The results show that the disparities in the blood group profiles of the general population, infected patients, survivors and deceased are marked enough to infer that ABO and Rhesus blood groups could be a factor in the infection and survival of Ebola Virus Disease (EVD)

Keywords: Ebola Virus Infection; ABO blood group; Rhesus blood group

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