Journal of Veterinary Science & Medical Diagnosis ISSN: 2325-9590

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Research Article, J Vet Sci Med Diagn Vol: 2 Issue: 2

Efficacy of Canine Influenza Virus (H3N8) Vaccine to Reduce Pulmonary Lesions after Co-challenge with Canine Influenza Virus and Streptococcus equi subsp. zooepidemicus

Jamie N Henningson1*, Laurie J Larson1, Marie E Pinkerton1, Patricia Sharp1, Bliss Thiel1, Muralidhar S Deshpande2, Tamara Davis2, Huchappa Jayappa2, Terri L Wasmoen2, Nallakannu Lakshmanan2 and Ronald D Schultz1
1University of Wisconsin-Madison, School of Veterinary Medicine, Department of Pathobiological Sciences, 2015 Linden Drive West, Madison, WI 53706, USA
2Merck Animal Health, 21401 West Center Road, Elkhorn, NE 68022, USA
Corresponding author : Jamie N Henningson, DVM, PhD
Kansas State University, College of Veterinary Medicine, Kansas State Veterinary Diagnostic Laboratory, 1800 Denison Ave., Manhattan, KS 66506, USA
Tel: 785-532-4129; Fax: 785-532-4481
E-mail: [email protected]
Received: April 23, 2013 Accepted: July 08, 2013 Published: July 12, 2013
Citation: Henningson JN, Larson LJ, Pinkerton ME, Sharp P, Thiel B, et al. (2013) Efficacy of Canine Influenza Virus (H3N8) Vaccine to Reduce Pulmonary Lesions after Co-challenge with Canine Influenza Virus and Streptococcus equi subsp. zooepidemicus. J Vet Sci Med Diagn 2:2. doi:10.4172/2325-9590.1000111

Abstract

Efficacy of Canine Influenza Virus (H3N8) Vaccine to Reduce Pulmonary Lesions after Co-challenge with Canine Influenza Virus and Streptococcus equi subsp. zooepidemicus

To examine the effectiveness of canine influenza vaccination to reduce pulmonary lesions in dogs co-challenged with CIV and S. equi subsp. zooepidemicus.In this study, four groups of 7- to 10-week-old, CIV-naive beagles (32 dogs total) were used. One group was vaccinated with CIV vaccine (group 4) and the remaining 3 groups (groups 1, 2 and 3) were not vaccinated. Group 1 was challenged with CIV, group 2 was challenged with S. equi subsp. zooepidemicus and groups 3 and 4 were co-challenged with CIV and S. equi subsp. zooepidemicus.

Keywords: Canine influenza vaccine; Influenza virus; Streptococcus equi subsp.zooepidemicus

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