Short Communication, J Clin Exp Onco Vol: 12 Issue: 6
Exploring the Occurrence and Effects of Skin Cancer
Eldine Gieng*
1Department of Oncology, Nanjing University of Chinese Medicine, Nanjing, China
*Corresponding Author: Eldine Gieng,
Department of Oncology, Nanjing
University of Chinese Medicine, Nanjing, China
E-mail: eldine_gieng@nucm11.cn
Received date: 22 November, 2023, Manuscript No. JCEOG-24-124739;
Editor assigned date: 24 November, 2023, Pre QC No. JCEOG-24-124739 (PQ);
Reviewed date: 08 December, 2023, QC No. JCEOG-24-124739;
Revised date: 15 December, 2023, Manuscript No. JCEOG-24-124739 (R);
Published date: 22 December, 2023, DOI: 10.4172/2324-9110.1000386
Citation: Gieng E (2023) Exploring the Occurrence and Effects of Skin Cancer. J Clin Exp Oncol 12:6.
Description
Surrounded by the warmth of sunlight, skin is a testament to the beauty of exposure to the sun's rays. However, this radiant relationship with sunlight also carries shadows that manifest in the form of skin cancer. It takes a deep dive into the occurrence and effects of skin cancer, shedding light on the intricacies of this pervasive health concern [1]. Skin cancer, the abnormal growth of skin cells, is a prevalent condition with varying types. The most common forms include Basal Cell Carcinoma (BCC), Squamous Cell Carcinoma (SCC), and melanoma. The occurrence of skin cancer is often linked to Ultraviolet (UV) radiation exposure from the sun or artificial sources, such as tanning beds [2].
Prolonged exposure to UV radiation is a primary contributor to skin cancer occurrence. UV rays can damage the DNA in skin cells, triggering mutations that lead to uncontrolled cell growth. This is particularly evident in areas of the body frequently exposed to sunlight, such as the face, neck, arms, and hands [3]. Geographical location and demographic factors play a role in skin cancer occurrence. Regions with high UV index levels, proximity to the equator, and lighter-skinned populations have higher rates of skin cancer. However, it's essential to note that individuals of all skin tones can develop skin cancer [4].
While UV exposure is a leading factor, genetic predisposition also plays a role in skin cancer occurrence. Individuals with a family history of skin cancer may have an increased risk, emphasizing the complex interplay between genetic and environmental factors. The effects of skin cancer extend beyond the physical realm, impacting not only the skin but also the emotional and psychological well-being of affected individuals [5]. The physical effects of skin cancer can range from relatively mild to severe. Basal cell carcinoma and squamous cell carcinoma, while generally less aggressive than melanoma, can cause disfigurement if left untreated. Melanoma, on the other hand, is more likely to metastasize, posing a greater threat to health [6].
Treatment for skin cancer often involves surgical procedures, such as Excision or Mohs surgery, to remove cancerous tissue. In some cases, additional therapies like radiation or immunotherapy may be necessary. These treatments can leave scars and may require ongoing surveillance, impacting a person's physical appearance and lifestyle [7]. Beyond physical scars, the emotional and psychological effects of skin cancer can be profound. The diagnosis and treatment process can evoke fear, anxiety, and concerns about body image. Individuals may grapple with the emotional impact of facing mortality and the uncertainty of the future [8].
Understanding the occurrence and effects of skin cancer underscores the importance of preventive measures. Empowering individuals with knowledge and promoting sun-safe behaviors can significantly reduce the risk of skin cancer [9]. Practicing sun protection is paramount in preventing skin cancer. This includes wearing protective clothing, using broad-spectrum sunscreen, and seeking shade during peak sunlight hours. Sun-protective measures are essential for individuals of all ages and skin types [10].
Regular self-examinations and professional skin checks are essential for early detection. By becoming familiar with the moles, freckles, and other skin markings, individuals can identify changes that may signal the development of skin cancer. Artificial sources of UV radiation, such as tanning beds, contribute to skin cancer risk [11]. Avoiding these sources and opting for sunless tanning alternatives can reduce the harmful effects of UV exposure.
Conclusion
As one can navigate the sunlit landscapes of the lives, it is essential to be aware of the shadows that lurk in the form of skin cancer. Exploring the occurrence and effects of skin cancer emphasizes the need for a multifaceted approach to prevention, encompassing sun protection, regular screenings, and a commitment to raising awareness. By embracing sun-safe behaviors and fostering a culture of skin health, one can collectively work towards reducing the incidence of skin cancer and ensuring a brighter, healthier future for generations to come.
References
- Boericke W (2004) Homeopathic materia Medica USA: Kessinger Publishing; 1:95–103.
- Bishayee K, Mukherjee A, Paul A, Khuda-Bukhsh AR (2012) Homeopathic mother tincture of Conium initiates reactive oxygen species mediated DNA damage and makes HeLa cells prone to apoptosis. Int J Genuine Tradit Med 2:37-41.
- Vetter J (2004) Poison hemlock (Conium maculatum L) Food Chem Toxico 42(9):1373-1382.
- Hussain AR, Ahmed SO, Ahmed M, Khan OS, Al Abdul Mohsen S, et al. (2012) Cross-talk between NFkB and the PI3-kinase/AKT pathway can be targeted in primary effusion lymphoma (PEL) cell lines for efficient apoptosis. Plosone 7(6):e39945.
- Singh BN, Shankar S, Srivastava RK (2011) Green tea catechin, epigallocatechin-3-gallate (EGCG): mechanisms, perspectives and clinical applications. Biochem Pharmacol 82(12):1807-21.
- Choudhuri NM (2014) A study on Materia Medica; B. jain publishers pvt ltd; 11th impression. 335-337.
- 7.Russell RC, Williams NS, Bulstrode CJ, Bailey H, Love RJ, et al. (2000) Bailey and Love's short practice of surgery.
- Gey G (1952) Tissue culture studies of the proliferative capacity of cervical carcinoma and normal epithelium. Cancer Res 12:264-265.
- Igarashi M, Miyazawa T (2001) The growth inhibitory effect of conjugated linoleic acid on a human hepatoma cell line, HepG2, is induced by a change in fatty acid metabolism, but not the facilitation of lipid peroxidation in the cells. Biochim Biophys Acta 1530(2-3):162-71.
- Skehan P, Storeng R, Scudiero D, Monks A, McMahon J, et al. (1990) New colorimetric cytotoxicity assay for anticancer-drug screening. J Natl Cancer Inst 82(13):1107-12.
- Patrawala L, Calhoun-Davis T, Schneider-Broussard R, Tang DG (2007) Hierarchical organization of prostate cancer cells in xenograft tumors: the CD44+ α2β1+ cell population is enriched in tumor-initiating cells. Cancer Res.67(14):6796-6805.