Editorial, J Liver Disease Transplant Vol: 9 Issue: 2
Journal of Liver Diseases and Transplantation Editorial Note
Associate Professor of Internal Medicine (Digestive Diseases), Yale University, Austria
Associate Professor of Internal Medicine (Digestive Diseases), Yale University, Austria.
E-mail: [email protected]
Received: April 25, 2020 Accepted: May 03, 2020 Published: May 10, 2020
Keywords: Liver Biology, Liver Cancers, Liver Cirrhosis, Liver Disease Complications,Liver Disease Diagnosis, Liver Failure, Liver Functions
Journal of Liver: Disease & Transplantation (JLDT) is a peerreviewed scholarly journal which aims to publish the most complete and reliable source of information on the discoveries and current developments in the mode of original articles, review articles, case reports, short communications, etc. in all areas of liver pathology and making them available online. For the last 12 years, published papers has be under the strong and able leadership of our Editor-in-Chief’s Dr. Carlo Spirli, PHD, Especially, we are thankful to Editor-in-Chief Dr. Carlo Spirli, also he is a Assistant Professor at the Department of Internal Medicine, Yale School of Medicine, USA for his continuous support and dedication towards the journal will not lost. We the publication office of Journal of Liver: Disease & Transplantation including me, we all are very honored and grateful for his selfless devotion towards the journal. We provide a rapid turn-around time possible for peer reviewing and publishing the article online and to disseminate the articles freely for research, teaching and reference purposes.
Scope of the journal
The scope includes Liver Failure, Liver Complications, Liver Cirrhosis, Liver Physiology, Liver Pathology, Fatty Liver, Gastrointestinal Disorders, Liver Genetics, Autoimmune Liver Diseases, Liver Transplantation, Post transplantation Care.
The study of functions and activities of the liver is known as Liver Physiology. It also deals with the way in which the Liver and its parts function
Functions of the liver include: Production of Bile, which helps carry away waste and break down fats in the small intestine during digestion, Production of proteins for blood plasma and detoxification of blood.
The study of Liver diseases is called Liver pathology. Liver diseases can be inherited or caused by a variety of factors that damage the liver, such as viruses and alcohol use. Liver diseases include the following conditions: Cirrhosis, Inflammation or hepatitis.
Liver disease diagnosis
Liver disease can often be difficult to diagnose because its symptoms can be vague and easily confused with other health problems. Blood tests can look for the presence of liver inflammation or screen for antibodies or virus particles that might indicate a specific form of liver Disease. These tests are called Liver Tests.
The fundamental concept underlying the Translational Hepatology is that human disease can serve as a window into broad biological processes, the understanding of which could, in turn, lead to treatments for these and other diseases.
Complications of a liver transplant can include rejection, an increased risk of infection, graft failure, biliary conditions and a higher risk of developing certain conditions – including some types of cancer.
Transplantation & immunosuppressive management
Immunosuppression involves an act that reduces the activation or efficacy of the immune system. Some portions of the immune system itself have immunosuppressive effects on other parts of the immune system, and immunosuppression may occur as an adverse reaction to treatment of other conditions
Post transplantation Care
After liver transplantation care must be taken because the complications don’t arise soon after the transplantation. They may arise after 2 or 3 weeks. Hence patients must be shifted to ICU and must be under observation. This is known as Post Transplantation care.
Liver failure is a life-threatening condition that demands urgent medical care. Most often, liver failure occurs gradually and over many years. Rare condition known as acute liver failure occurs rapidly within 48hrs and difficult to detect initially.
The liver has a remarkable capacity to regenerate after injury and to adjust its size to match its host. Within a week after partial hepatectomy, which, in typical experimental settings entails surgical removal of two-thirds of the liver, hepatic mass is back essentially to what it was prior to surgery
Liver disease complications
These include high blood pressure in the veins that supply the liver, swelling inthe legs and abdomen, enlargement of spleen, bleeding, infections, malnutrition, jaundice, bone diseases, increased risk of liver cancer and acute-or-chronic cirrhosis.
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