International Journal of Ophthalmic PathologyISSN: 2324-8599

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Case Report, Int J Ophthalmic Pathol Vol: 5 Issue: 1

Lacrimal Gland Metastasis and Paraneoplastic Orbital Myositis due to Breast Carcinoma

Pinar Bingol Kiziltunc1*, Huban Atilla2, Cenk Akbostanc�?±3, Canan Togay Isikay3 and Omur Ataoglu4
1Department of Ophthalmology, Kagizman State Hospital, Kars/Turkey
2Department of Ophthalmology, Ankara University, Ankara, Turkey
3Department of Neurology, Ankara University, Faculty of Medicine, Ankara, Turkey
4Department of Pathology, Mikro-pat Pathology Laboratory, Ankara, Turkey
Corresponding author : Pinar Bingol Kiziltunc, MD
Department of Ophthalmology, Kagizman State Hospital, Kars/Turkey
Tel: +90 544 821 41 53
Fax: +90 474 351 64 53
Received: January 12, 2016 Accepted: May 02, 2016 Published: May 08, 2016
Citation: Kiziltunc PB, Atilla H, Akbostanci C, Isikay CT, Ataoglu O (2016) Lacrimal Gland Metastasis and Paraneoplastic Orbital Myositis due to Breast Carcinoma. Int J Ophthalmic Pathol 5:1. doi:10.4172/2324-8599.1000177


We present a case with lacrimal gland metastasis and paraneoplasticorbital myositis due to breast carcinoma. A 66 year-old woman with a history of breast carcinoma was seen with the complaints of headache, blurred vision, and diplopia. On neuro-ophthalmologic examination restriction of left, right and up gaze in her left eye was found. Magnetic resonance imaging of orbit revealed enlargement of all extraocular muscles, heterogeneous enhancement of lacrimal gland and retroorbital fat in her left eye. The patient underwent biopsy of lacrimal gland and extraocular muscles. Lacrimal gland metastasis was shown by histopathologic examination, but there was no tumor cells in the extraocular muscles. After radiotherapy for lacrimal gland metastasis, her symptoms relieved remarkably. In patients with a history of malignancy, orbital symptoms and findings should be thought as a cause of malignancy primarily.

Keywords: Breast carcinoma; Lacrimal gland; Metastasis; Paraneoplastic syndrome; Orbital myositis

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