Analgesia & Resuscitation : Current ResearchISSN: 2324-903X

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Short Article, Analg Resusc Curr Res Vol: 7 Issue: 2

Modulation of TRP Activation and Nerve Conduction for Analgesia

Eiichi Kumamoto*, Tsugumi Fujita, Rika Suzuki, Nobuya Magori and Chong Wang

Department of Physiology, Saga Medical School, 5-1-1 Nabeshima, Saga 849- 8501, Japan

*Corresponding Author : Eiichi Kumamoto
Department of Physiology, Saga Medical School, 5-1-1 Nabeshima, Saga 849-8501, Japan
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81-952-34-2275
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Received: February 26, 2018 Accepted: March 06, 2018 Published: March 12, 2018

Citation: Kumamoto E, Fujita T, Suzuki R, Magori N, Wang C (2018) Modulation of TRP Activation and Nerve Conduction for Analgesia. Analg Resusc: Curr Res 7:2. doi:10.4172/2324-903X.1000159

Abstract

Antinociception is produced as a result of various actions including the modulation by analgesics of transient receptor potential (TRP) channel activation and nerve conduction. Elucidation of such a modulation produced by analgesics may serve to understand a cellular mechanism for antinociception.

Keywords: TRPV1; TRPM8; TRPA1; Synaptic transmission; L-Glutamate; Spinal substantia gelatinosa; Dorsal root ganglion; Nerve conduction; Analgesia

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