Journal of Spine & NeurosurgeryISSN: 2325-9701

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Research Article, J Spine Neurosurg Vol: 6 Issue: 5

Streptococcus parasanguinis as Cause of Odontogenic Brain Abscess

Alessandro Frati1, Alessandro Pesce2,3*, Giada Toccacelib3, Michele Acqui2,3, Riccardo Caruso4, Maurizio Salvati1 and Antonino Raco2,3

1IRCCS “Neuromed”, Via Atinense 18, 86077, Pozzilli (IS), Italy

2A.O. “Sant’Andrea”, Neurosurgery Division, Via di Grottarossa, 1035 1039 00189, Roma, Italy

3NESMOS Department, “Sapienza” University, Roma, Italy

4Neurology and Psychiatry Department, Neurosurgery Division, “Sapienza” University, Roma, Italy

*Corresponding Author : Dr. Alessandro Pesce
A.O. “Sant’Andrea”, Neurosurgery Division, Via di Grottarossa, 1035-1039 00189, Roma, Italy
Tel: +393408094246
Fax: +390633775378

Received: October 22, 2017 Accepted: December 15, 2017 Published: December 29, 2017

Citation: Frati A, Pesce A, Toccacelib G, Acqui M, Caruso R, et al. (2017) Streptococcus parasanguinis as Cause of Odontogenic Brain Abscess. J Spine Neurosurg 6:5. doi: 10.4172/2325-9701.1000288


Brain abscess (BA) is a serious life threatening condition, usually fatal if left untreated. Despite the continuous advances in antibiotic therapy and in technologies for surgical treatment, the mortality rate is still as high as 10% in western countries and up to 32% in the developing countries. The most common pathogenetic mechanisms of intracranial abscesses are the following: infection caused by penetrating cranial trauma and/or neurosurgical procedure, hematologic dissemination by distant abscesses, dissemination for continuity by proximal abscesses as otitis, sinusitis, periodontal pathology and dental abscesses. Odontogenic origin of a brain abscess is an uncommon finding. The aim of this study is to report an odontogenic brain abscess sustained by Streptococcus Parasanguinis strain, a microorganism thought to initiate dental plaque, capable of sustaining endocarditis but never described in literature as cause of brain abscess.

Keywords: Brain; Brain abscess; Streptococcus; Odontogenic; MRI

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