Journal of Diagnostic Techniques and Biomedical Analysis.ISSN: 2469-5653

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Research Article,  J Diagn Tech Biomed Anal Vol: 9 Issue: 2

The Correlation between Chest CT and Quantitative RT-PCR Results for COVID-19 Diagnosing in Iran

Emran Esmaeilzadeh1, Nasrollahzadeh Sabet1*, Mohammad Foad Heidari2, Mohammad Khanalipou1, MiladJafari Ashiani3 and Mohammad-Taher Moradi4

1School of Medicine, AJA University of Medical Science, Tehran, Iran

2Department of Medical Laboratory Sciences, School of Allied Health Medicine, AJA University of Medical Sciences, Tehran, Iran

3Golestan Hospital, Tehran, Iran

4Medical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran

*Corresponding Author : Sabet MN School of Medicine, AJA University of Medical Science, Tehran, Iran Tel: +9843822368 E-mail: E-mail: [email protected]

Received: May 22, 2020 Accepted: June 08, 2020 Published: July 04, 2020

Citation: Esmaeilzadeh E, Sabet MN*, Heidari FM, Khanalipou M, Ashiani M et al. (2020) The Correlation between Chest CT and Quantitative RT-PCR Results for COVID-19 Diagnosing in Iran. J Diagn Tech Biomed Anal 9:2. doi: 10.37532/jdtba.2020.9(2).143

Abstract

The aim of this study was the assessment of chest CT and quantitative RT-PCR reliabilities in diagnosing COVID-19 pneumonia in Iran. This retrospective study was conducted on 740 COVID-19 suspected cases from 15 February to 5 April 2020, which had both CT and RT-PCR. The efficiency of chest CT for COVID-19 detection had been assessed in comparison to RT-PCR as the reference test. Among 740 cases, 637(86.1%) had positive chest CT and 455 patients (61.5%) had positive RT-PCR results. With RT-PCR as the reference test, the sensitivity of chest CT was 89.45%. According to the results, RT-PCR may produce initial false-negative results, suggesting that patients with positive chest CT but negative RT-PCR may be the disease carrier and should be isolated.

Keywords: CT-scan; RT-PCR; COVID-19

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