Journal of Virology & Antiviral ResearchISSN: 2324-8955

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Research Article, J Virol Antivir Res Vol: 7 Issue: 1

Treatment of Hepatitis C Virus Infection with Sovaldi Drug among Patients in Sohag Government, Egypt

AEl-Adly AM1*, Rashed LA2, Yehia HM2, Wardany AA1, Shikhoun MH1 and Abdul-Raouf UM1

1Faculty of Science, Microbiology Department, Al-Azhar University, Assiut, Egypt

2Faculty of Medicine, AL- Kaser Al-Any Hospital, Cairo University, Cairo, Egypt

*Corresponding Author : El-Adly AM
Faculty of Science, Botany and Microbiology Department, Al-Azhar University, Assiut, Egypt
Tel: +01147787828

Received: March 19, 2018 Accepted: March 28, 2018 Published: April 04, 2018

Citation: AEl-Adly AM, Rashed LA, Yehia HM, Wardany AA, Shikhoun MH, et al. (2018) Treatment of Hepatitis C Virus Infection with Sovaldi Drug among Patients in Sohag Government, Egypt. J Virol Antivir Res 7:1. doi: 10.4172/2324-8955.1000181


Background: Hepatitis C virus (HCV) is one of the hepatitis viruses that are transmitted through blоod or blоod products. HCV has been implicated as a major reason of chronic liver disease and hepatоcellular carcinoma worldwide. 
Aim: Should be to determine the responses of patients infected with HCV to sovaldi drug in Sohage governorate, Egypt. 
Method: We randomly selected 50 patients from males and females at different ages, all patients from Sohage governorate, Egypt. All patients were treated with Sovaldi drug and detection should be who responded and non-responded to treatment by using RT- PCR technology and should be biochemical tests.
Results: Our results showed that, among 50 patients infected with hepatitis C virus and treated with sovaldi drug 25/50 (50 %) were responded to sovaldi treatment, while other showed non-responded to treatment. All patients aged between 30 to 55 years, where 13(26%) cases of females and 37(74%) cases of males. Respond to treatment with sovaldi drug associated with gender and age, female were more respond to sovaldi compared as male, and patients aged from 40-45 years were more respond 11/25 (44%) than patient aged from 45-55.
Conclusion: This study was conducted to determine the role of sovaldi drug to treated patients infected with sovaldi drug. It is our hope that the data generated will be an addition to the existing pool of HCV data available in the Egypt. 

Keywords: Hepatitis C virus; Antibody; Sovaldi; Sohag; Risk factors

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