Journal of Veterinary Science & Medical Diagnosis ISSN: 2325-9590

Research Article, J Vet Sci Med Diagn Vol: 5 Issue: 6

Utility of Skin Biopsy Sample for Rabies Diagnosis in Dogs

Gowri Yale1*, Reeta Subramaniam Mani2, Patchimuthu I. Ganesan1, Shampur Narayan Madhusudana2, Anita Mahadevan3, Susarla K. Shankar3, Mangalanathan Vijayabharathi1, Sampada Sudarshan2 and Shaheen Taj2
1Department of Veterinary Epidemiology and Preventive Medicine, Madras Veterinary College, Vepery, Chennai – 600 007, India
2Department of Neurovirology, WHO Collaborating Centre for Reference and Research on Rabies, National Institute of Mental Health and Neurosciences, Bangalore – 560 029, India
3Department of Neuropathology, National Institute of Mental Health and Neurosciences, Bangalore – 560 029, India
Corresponding author : Gowri Yale
PhD Scholar, Department of Veterinary Epidemiology and Preventive Medicine, Madras Veterinary College, Vepery, Chennai – 600 007, India
E-mail: [email protected]
Received: August 29, 2016 Accepted: September 30, 2016 Published: October 06, 2016
Citation: Yale G, Mani RS, Ganesan PI, Madhusudana SN, Mahadevan A, et al. (2016) Utility of Skin Biopsy Sample for Rabies Diagnosis in Dogs. J Vet Sci Med Diagn 5:6. doi: 10.4172/2325-9590.1000213

Abstract

Utility of Skin Biopsy Sample for Rabies Diagnosis in Dogs

Background: Rabies is endemic to India and is the most feared disease of all times. Dogs are the main vectors of rabies in India contributing to more than 90% of human rabies cases. Presently, confirmatory diagnosis of rabies in dogs is done by fluorescent antibody test (FAT) on brain tissue from a dead dog. However, obtaining brain tissue by necropsy poses several hazards and hence there is a need to evaluate alternative methods for diagnosis of canine rabies. The present study evaluated the utility of nuchal skin biopsy sample for the detection of rabies in dogs.

Keywords: Rabies virus; Canine; Nuchal skin; RT-PCR; Immunohistochemistry; Diagnosis

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