Journal of Spine & NeurosurgeryISSN: 2325-9701

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Case Report, J Spine Neurosurg Vol: 4 Issue: 5

Vertebra Plana due to Thalassemia: A Case Report

Mehmet Secer1*, Murat Ulutas2, Oktay Tosun3, Bahadir Okten4 and Kadir Cinar2
1Department of Neurosurgery, Deva Hospital, Gaziantep, Turkey
2Department of Neurosurgery, Konukoglu Hospital, Sanko University, Gaziantep, Turkey
3Department of General Surgery, Deva Hospital, Gaziantep, Turkey
4Department of Anesthesiology, Deva Hospital, Gaziantep, Turkey
Corresponding author: Mehmet Secer
Department of Neurosurgery, Deva Hospital, Gaziantep, Turkey
Tel: +905053478955; Fax: +90342 3241852
Received: October 15, 2015 Accepted: December 11, 2015 Published: December 17, 2015
Citation: Secer M, Ulutas M, Tosun O, Okten B, Cinar K (2015) Vertebra Plana due to Thalassemia: A Case Report. J Spine Neurosurg 4:5. doi:10.4172/2325-9701.1000204


Beta thalassemia syndromes are a group of hereditary blood disorders causing a reduction of hemoglobin (Hb) content of red blood cells due to reduced or absent β globin chain synthesis. Beta thalassemia major emerges between 6th and 24th months of life and is characterized by growth retardation, pallor, jaundice, muscular weakness, genu valgum, hepatosplenomegaly, foot ulcers, mass lesions due to extramedullary hematopoiesis, and skeletal changes secondary to bone marrow expansion [1]. A normal growth rate can be achieved for 10 to 12 years provided that hemoglobin concentration is kept between 9.5 and 10.5 g/dl by regular blood transfusions [2]. In patients undergoing transfusions certain complications secondary to excessive iron loading may occur and include delayed sexual maturation, cardiomyopathy, endocrine gland dysfunction, hypersplenism, chronic hepatitis, HIV infection, venous thrombosis, and osteoporosis [1,3]. Vertebra plana is a radiological diagnosis defined as vertebral flattenLnJ or straightening with preserved intervertebral disc height. It arises most commonly due to eosinophilic granuloma while metastatic disease, multiple myeloma, lymphoma, leukemia, Ewing’s sarcoma, Gaucher disease, tuberculosis, and aneurysmal bone cysts are other causes [4]. НalassemLa major, on the other hand, is not a frequent cause of vertebra plana. НLs paper discusses the etiopathogenesis and management approach of osteoporosis-induced vertebra plana of L4 vertebra in a case with thalassemia major.

Keywords: Vertebra, hemoglobin

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