Journal of Molecular Medicine & Therapeutics#

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Research Article, Mol Med Ther Vol: 1 Issue: 2

Performance of Commercial Interferon-γ Release Assays for Screening Latent Tuberculosis Infection: A Meta-Analysis

Lin Sun1, Qingqin Yin1, Jianling Tian1, Qing Miao1, Fang Xu1, Jing Xiao1, Chen Shen1, Weiwei Jiao1, Cornelia Lass-Flörl2, Aamir Shahzad3 and Adong Shen1*
1Key Laboratory of Major Diseases in Children (Capital Medical University), Ministry of Education, Beijing Pediatric Research Institute, Beijing Children’s Hospital affiliated to Capital Medical University, 56 Nan Li Shi Road, Xi Cheng District, Beijing 100045, China
2Department of Hygiene, Microbiology and Social Medicine, Innsbruck Medical University, Innsbruck, Austria
3Department of Structural and Computational Biology, University of Vienna, Vienna, Austria
Corresponding author : Dr. Adong Shen
Key Laboratory of Major Diseases in Children (Capital Medical University), Ministry of Education, Beijing Pediatric Research Institute, Beijing Children’s Hospital affiliated to Capital Medical University, 56 Nan Li Shi Road, Xi Cheng District, Beijing 100045, China
E-mail: [email protected]
Received: October 30, 2012 Accepted: November 28, 2012 Published: December 05, 2012
Citation: Sun L, Yin Q, Tian J, Miao1 Q, Xu F, et al. (2012) Performance of Commercial Interferon-? Release Assays for Screening Latent Tuberculosis Infection: A Meta-Analysis. Mol Med Ther 1:2. doi:10.4172/2324-8769.1000103

Abstract

Performance of Commercial Interferon-γ Release Assays for Screening Latent Tuberculosis Infection: A Meta-Analysis

This meta-analysis was performed to systematically evaluate two interferon gamma release assays (IGRAs): ELISA and ELISPOT along with Tuberculin Skin Test (TST) in the detection of latent tuberculosis infection.

Keywords: Meta-analysis; Interferon gamma; Diagnosis; Tuberculosis

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