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Journal of Spine & NeurosurgeryISSN: 2325-9701

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Research Article, J Spine Neurosurg S Vol: 0 Issue: 0

Postoperative Ambulatory Status Predicts Survival in Patients with Glioblastoma Multiforme

Leif-Erik Bohman1, James H Stephen1, Rohan Ramakrishna2, James M Schuster1 and Neil R Malhotra1*
1Department of Neurosurgery, University of Pennsylvania, Philadelphia, PA, USA
2Department of Neurological Surgery, University of Washington, Seattle, WA, USA
Corresponding author : Neil R Malhotra, MD
Assistant Professor, Department of Neurosurgery, University of Pennsylvania, 3 Silverstein - 3400 Spruce Street, Philadelphia, PA 19104, USA
E-mail: [email protected]
Received: April 12, 2013 Accepted: May 10, 2013 Published: May 31, 2013
Citation: Bohman LE, Stephen JH, Ramakrishna R, Schuster JM, Malhotra NR (2013) Postoperative Ambulatory Status Predicts Survival in Patients with Glioblastoma Multiforme. J Spine Neurosurg S1. doi:10.4172/2325-9701.S1-001

Abstract

Postoperative Ambulatory Status Predicts Survival in Patients with Glioblastoma Multiforme

Much attention in the surgical literature has emphasized the survival benefit of maximal resection in patients with Glioblastoma Multiforme (GBM). Preoperative functional status has also been long recognized as a major factor on prognosis, but less attention has been paid to the importance of postoperative neurological function on survival. Our study sought to investigate the survival impact of a particularly severe postoperative motor deficit, the loss of functional ambulation, on survival in patients with newly diagnosed primary GBM.

Keywords: Gliomas; Glioblastoma; Survival; Ambulatory status; Ambulation; Prognosis; Extent of resection

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