Journal of Virology & Antiviral ResearchISSN: 2324-8955

Research Article, J Virol Antivir Res Vol: 2 Issue: 4

Prevalence of Hepatitis Virus and HBV/HCV Interactions in Opiate Addict Subjects

Fabio Curcio1* and Clara Baldassarre2
1Centro Clinico Farmacodipendenze, Italy
2Director Centro Clinico Farmacodipendenze, Italy
Corresponding author : Fabio Curcio
Via Ferdinando Russo, 29 80123 Napoli, Italy
Tel: +39 3356744071; Fax: +39 081 2548109
E-mail: [email protected]
Received: August 11, 2013 Accepted: December 10, 2013 Published: December 13, 2013
Citation: Curcio F, Baldassarre C (2013) Prevalence of Hepatitis Virus and HBV/HCV Interactions in Opiate Addict Subjects. J Virol Antivir Res 2:4. doi:10.4172/2324-8955.1000115

Abstract

Prevalence of Hepatitis Virus and HBV/HCV Interactions in Opiate Addict Subjects

Aims of the study were: 1) the assessment of the prevalence of HBV, HCV and HDV infections in opiate addict subjects; 2) the study of the viral interaction in vivo. Method: The study evaluated HBV and HCV infections in 1682 subjects assisted from 1990 to 2010. Outcomes: In 2010 the prevalence of HBV infection was of 42.3%; the number of HBs Ag carrier subjects was of 4,4%. HCV infection prevalence rose of 60.4%. The prevalence of the co-infection HBV/HCV was of 32.0%; during the co-infection phase, HBV infection spread earlier with a 2.8 higher probability than HCV infection. The RNA of HCV virus was positive in 25.9% of the cases of HBsAg carrier subjects. The RNA of HCV resulted to be positive among HBV infected subjects compared to HBV carrier subjects with O.R. 10.47.

Keywords: HBV; HCV; Co-infection; Viral interference; Prevalence; HDV, Journal of Virology & Antiviral Research, Fabio Curcio, Clara Baldassarre, research article, scholarly articles, open access

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