Research Article, J Virol Antivir Res Vol: 4 Issue: 3
Prevalence of Viral Hepatitis B and C Markers in Multitransfused Patients with Chronic Kidney DiseaseCompared with The General Population in Albania
|Tatjana Nurka1*, Erika Ebranati2, Robert Çina3, Zhaneta Abazi4, Anila Kristo5, Xhensila Frasheri1, Vjollca Shpata1, Pranvera Dragusha6, Massimo Ciccozzi7, Gianguglielmo Zehender2 and Renata Shkjezi6|
|1Department of Medical and Technical Science, University of Medicine, Tirana, Albania|
|2Department of Biomedical and Clinical Sciences “L. Sacco”, University of Milan, Italy|
|3University of Sports of Tirana, Albania|
|4National Blood Transfusion Centre, Tirana, Albania|
|5Faculty of Medicine, University of Medicine, Tirana, Albania|
|6Faculty of Medicine, Catholic University “Our Lady of Good Council”, Tirana, Albania|
|7Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanità, Rome, Italy|
|Corresponding author : Tatjana Nurka
University of Medicine, Tirana, Faculty of Medical and Technical Science,Kongresi Manastirit 133,1005, Tirana, Albania
|Received: August 01, 2015 Accepted: September 01, 2015 Published: September 07, 2015|
|Citation: Nurka T, Ebranati E, Çina R, Abazi Z, Kristo A, et al. (2015) Prevalence of Viral Hepatitis B and C Markers in Multitransfused Patients with Chronic Kidney Disease Compared with The General Population in Albania. J Virol Antivir Res 4:3. doi:10.4172/2324-8955.1000142|
Evaluation of the prevalence of viral hepatitis markers in CKD patients and comparison with the prevalence in family replacement donors as a control group of the general population in Albania.
64 patients with CKD treated with three or more blood transfusions were evaluated for Hepatitis B and C markers. They were divided in hemodialysed (HD) and non-hemodialysed (Non- HD) patients. We compared the prevalence of HBV and HCV markers founded in these patients with those of blood donors group which includes 1993 subjects divided in two categories: regular blood donors 625 subjects and family replacement donors 1368 subjects, the later being considered as control group.
The prevalence of viral hepatitis B and C markers found in CKD patients were significantly higher than those of the control group (27% and 31% vs 8.5% and 2%). There are no significant differences of HBsAg prevalence in HD and Non-HD patients, but there is a significant one in the presence of anti HCV in HD patients. We also assessed the impact of age and temporal duration of hemodialysis in this prevalence. We confirm that the prevalence of HCV and HBV markers is significantly higher in CKD compared to the general Albanian population.
The amount of blood transfusions and the age of patients are important risk factors for the spread of these infections.