Antibacterial potentials of the leaf extracts of Siam weed (Chromolaena odorata) on wound isolates

<p>ME Abalaka, OA Falusi, M Galaadima and FA Kuta</p>

Antibacterial potentials of the leaf extracts of Siam weed (Chromolaena odorata) on wound isolates

ME Abalaka, OA Falusi, M Galaadima and FA Kuta

Federal University of Technology, Nigeria

: J Regen Med

Abstract

The antimicrobial activity of aqueous, ethanolic and methanolic extracts of Chromolaena odorata (Siam weed) was evaluated against four wound isolates: Staphylococcus aureus, Escherchia coli, Pseudomonas aeruginosa and Klebsiella pneumoniae at the concentrations of 200mg/ml,100mg/ml,50mg/ml and 25mg/ml respectively. Staphylococcus aureus and E. coli showed high susceptibility to the various extracts than the other test isolates. The aqueous extract showed activity against Staphylococcus aureus with a mean diameter of zone of inhibition of 16±3.00 at concentration of 200mg/ml and as low as 8±0.00 at concentration of 25mg/ ml; E. coli showed susceptibility with a mean diameter of zone of inhibition of 18±2.00 and 10±0.00 at a concentration of 200mg/ml and 25mg/ml respectively. Pseudomonas aeruginosa and Klebsiella pneumoniae were resistant to the aqueous extract. Methanol extract showed activity against Staphylococcus aureus with a mean diameter of zone of inhibition at 28±4.00 and 12±2.30 at a concentration of 200mg/ml and 25mg/ml respectively; while E. coli was susceptible with mean diameter of zone of inhibition of 18±2.00 and as low as 12±0.00 at a concentration of 200mg/ml and 50mg/ml respectively, Pseudomonas aeruginosa showed considerable susceptibility with mean diameter of zone of inhibition of 13±1.00 and 12±0.00 at a concentration of 200mg/ml and 100mg/ml respectively. The ethanol extract showed activity against S. aureus with a mean diameter zone of inhibition of 15±2.00 and 9±0.00 at a concentration of 200mg/ml and 25mg/ml respectively: E. coli showed susceptibility with a mean diameter zone of inhibition of 20±4.00 and 13±2.00 at a concentration of 200mg/ml and 25mg/ml respectively. Pseudomonas aeruginosa showed considerable susceptibility with a mean diameter zone of inhibition of 13±1.00 and 9±0.00 at a concentration of 200mg/ml and 100mg/ml respectively. The results above indicate the efficacy and potency of the crude extracts of Chromolaena odorata leaf on the tested wound isolates.