Material development for Rapid Prototyping for futur medical application
Wolfdietrich Meyer, Kirsten Borchers, Esther Novosel, Petra Kluger, Nadine Nottrodt, Birgit Huber and Sascha Engelhardt
Fraunhofer Institute for Applied Polymer Research IAP, Potsdam 14476, Germany
Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Stuttgart 70569, Germany
Rheinisch-Westfälische Technische Hochschule Aachen, RWTH
: J Regen Med
Photocurable liquid monomers were crosslinked by laser irradiation to form cytocompatible, non-degradable polymers with adjustable mechanical properties to build up artifical blood vessel structures. The mechanical properies of the vessel-like material is mimicing the natural ideal and is ready to be biofunctionalized and seeded with epithelial cells in the inner side of the photopolymeric tube system. Similar a high porous and branched tubesystem is manufactured by stereolithograhy to find its application as blood supplying system for tissue engineering. Synthesis of model photoaktive crosslinker are indroduced that allow the adaptation of mechanics in photopolymers for artifical soft tissues. Mechanical studies regarding the elasticity, tear strength and tear tensile strength of the photopolymers are presented.
Wolfdietrich Meyer has completed his PhD in 2005 on Bioanalytical Electrochemistry. As a post doc he did research on nanoparticles applied for MRI contrast agents at the Charité in Berlin. From 2009 on he is focusing on material development for 3D printing for medical application at the Fraunhofer Institute for Applied Polymer Research.