The MPV is a new marker to predict the menopause


Havva Keskin, Yasemin Kaya, Kenan Cadirci, Hakan Gozcu, Elif Ziypak, Ayse Carlioglu and Senay Arikan

Istanbul Medeniyet University, Turkey
Ordu University, Turkey
Erzurum Regional Training and Research Hospital, Turkey
Kirikkale University,

: Endocrinol Diabetes Res

Abstract


Introduction & Aim: Systemic chronic inflammation causes atherosclerotic lesions and the Neutrophil-Lymphocyte Ratio (NLR) is an indicator of systemic inflammation. We found out the NLR was high in young male with Idiopathic Hypogonadotropic Hypogonadism (IHH). Systemic chronic inflammation causes atherosclerotic lesions and the Neutrophil-Lymphocyte Ratio (NLR) is an indicator of this systemic inflammation. Awareness of the inflammation in the young male with IHH is important to reduce the death rate in these patients. The aim of this study is to determine whether NLR was higher in male IHH patients. Method: A total of 33 IHH untreated patients and 56 age adjusted healthy controls were enrolled in this study. Blood sampling, anthropometric measures and physical examination were undertaken. Result: Neutrophils, NLR, CRP and UA levels of in the IHH group were slightly higher than control as inflammatory markers. This NLR was higher than the controls as independently from the fasting glucose, age and Body Mass Index (BMI) in hypogonadism patients Conclusion: Several systemic inflammatory markers and the NLR were higher in IHH patients. The NLR was also positively correlated with other inflammatory markers.

Biography


Havva Keskin is working on a Doctoral Program in Epidemiology and Data Management at Istanbul Medeniyet University Research Hospital, Turkey. She has completed her Residency at Ankara University Hospital. She has worked with Professor Philip R Taylor as a Guest Researcher and Fellow Assistant at National Institutes of Health (NIH), National Cancer Institute (NCI), Division of Cancer Epidemiology and Genetics, Metabolic Epidemiology Branch.

E-mail: havva.drkeskin@gmail.com

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