Cell Biology: Research & TherapyISSN: 2324-9293

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Research Article, Cell Biol Res Ther Vol: 4 Issue: 1

Protection against Carbon Tetrachloride-Induced Liver Damage by Citric Acid

Omar ME Abdel Salam1*, Amany A Sleem1 and Nermeen M Shaffie2*
1Department of Pharmacology, National Research Centre, Tahrir St., Dokki, Cairo, Egypt
2Department of Pathology, National Research Centre, Tahrir St., Dokki, Cairo, Egypt
Corresponding author : Omar ME Abdel Salam
Department of Pharmacology, National Research Centre, Tahrir St., Dokki, Cairo, Egypt
Tel: +2-0 2-33335996
E-mail: [email protected]
Received: Apr 02, 2015 Accepted: May 04, 2015 Published: May 11, 2015
Citation: Abdel Salam OME, Sleem AA, Shaffie NM (2015)Protection against Carbon Tetrachloride-Induced Liver Damage by Citric Acid. Cell Biol: Res Ther 4:1. doi:10.4172/2324-9293.1000116

Abstract

Citric acid (2-hydroxy-1,2,3-propane-tricarboxylic acid) is a weak organic acid found in the greatest amounts in citrus fruits such as lemon, grapefruit, tangerine and orange. Lemon and lime juice are rich sources of citric acid which contain 1.44 and 1.38 g/oz, respectively. Citric acid is used as a food additive, a natural preservative and to add an acidic sour taste to foods and soft drinks.

Keywords: Citric acid; Adrenergic blockade; Cholinergic blockade; Liver; Hepatoprotection; Rat; Vagotomy

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