Journal of Regenerative Medicine ISSN: 2325-9620

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Review Article, J Regen Med Vol: 3 Issue: 2

Stem Cell Therapy for Amyotrophic Lateral Sclerosis:Yesterday, Today and Tomorrow

Murat Kocaoglu1, Mevci Ozdemir1*, Veli Citisli1 and Kevser Ozdemir2
1Pamukkale University, Faculty of Medicine, Department of Neurosurgery, Denizli, Turkey
2Denizli State Hospital, Department of Infectious Diseases and Clinical Microbiology, Denizli, Turkey
Corresponding author : Mevci Ozdemir, MD
Associate Professor, Pamukkale University, Faculty of Medicine, Department of Neurosurgery, 20070, Kinikli, Denizli, Turkey
Tel: +90 258 444 0728; Fax: +90 258 213 4922
E-mail: [email protected]
Received: July 21, 2014 Accepted: December 02 2014 Published: December 08 2014
Citation: Kocaoglu M, Ozdemir M, Citisli V, Ozdemir K (2014) Stem Cell Therapy for Amyotrophic Lateral Sclerosis:Yesterday, Today and Tomorrow. J Regen Med 3:2. doi:10.4172/2325-9620.1000118

Abstract

Stem Cell Therapy for Amyotrophic Lateral Sclerosis:Yesterday, Today and Tomorrow

Amyotrophic lateral sclerosis (ALS) is a progressive motor neuron disease, which have no any effective treatment method. There are various pathophysiological processes underlying the disease such as oxidative stress, glutamate toxicity, inflammation and loss of the glial neurotrophic support. There is no cure yet for ALS but there are many clinical trials that focused different therapeutic targets. One of the most popular treatment methods is cell transplantation. The cellbased therapies are promising for ALS patients with many evidences including beneficial effects in protection neurons and replacement of degenerated neurons.

Keywords: Stem cell; Regeneration; Amyotrophic lateral sclerosis

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