Journal of Virology & Antiviral ResearchISSN: 2324-8955

Case Report, J Virol Antivir Res Vol: 2 Issue: 4

To Treat or Not to Treat? : A Case of Severe Acute Hepatitis-B Treated with Entecavir Compared to a Case of Milder, Untreated Disease

Maria Francesca Zenobii, Stefano Ballestri, Amedeo Lonardo*, Silvia Ognibene, Enrica Baldelli, Dante Romagnoli and Paola Loria
Dipartimento Integrato di Medicina, University of Modena and Reggio Emilia, Endocrinologia, Metabolismo e Geriatria, Modena, Italy
Corresponding author : Amedeo Lonardo, M.D
Dipartimento Integrato di Medicina, Endocrinologia, Metabolismo e Geriatria, UOC di Medicina Interna, Via Giardini 1355 41126, Modena, Italy
Tel: +39 059396807
E-mail: [email protected]
Received: November 22, 2013 Accepted: December 19, 2013 Published: December 23, 2013
Citation: Zenobii MF, Ballestri S, Lonardo A, Ognibene S, Baldelli E, Romagnoli D, Loria P, et al.(2013) “To Treat or Not to Treat?”: A Case of Severe Acute Hepatitis-B Treated with Entecavir Compared to a Case of Milder, Untreated Disease. J Virol Antivir Res 2:4. doi:10.4172/2324-8955.1000117

Abstract

“To Treat or Not to Treat?”: A Case of Severe Acute Hepatitis-B Treated with Entecavir Compared to a Case of Milder, Untreated Disease

Purpose: Acute hepatitis B, usually a benign disease in the immunocompetent adult, may be fatal in a minority of cases. The oral deoxyguanosine nucleoside analogue entecavir has gained a definite role in treating chronic hepatitis B virus infection. However, the indications and the specific timing for antiviral treatment in severe AHB remains to be established. We aimed at gaining insight into such indication based on clinical observation of two cases.

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