Journal of Regenerative MedicineISSN: 2325-9620

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Research Article, J Regen Med Vol: 4 Issue: 2

Use of Autologous Adipose- Derived Stromal Vascular Fraction to Treat Osteoarthritis of the Knee: A Feasibility and Safety Study

Jaime R Garza1*, Daniel Santa Maria2, Timothy Palomera2, Gregory A Dumanian3 and Severiano Dos-Anjos4
1School of Medicine, The University of Texas Health Science Center at San Antonio, Texas, USA
2Sports Medicine Associates of San Antonio, Texas, USA
3Neurologic Surgery and Orthopedic Surgery, Northwestern University- Feinberg School of Medicine, Chicago, Illinois, USA
4Stem-Center, Palma, Mallorca, Spain
Corresponding author : Jaime R. Garza, MD, DDS
21 Spurs Lane, Suite 120, San Antonio, Texas 78240, USA
Tel: 210-6160301; Fax: 210-6160302
E-mail: [email protected]
Received: December 23, 2014 Accepted: March 12, 2015 Published: March 16, 2015
Citation: Garza JR, Santa Maria D, Palomera T, Dumanian GA, Dos-Anjos S (2015) Use of Autologous Adipose-Derived Stromal Vascular Fraction to Treat Osteoarthritis of the Knee: A Feasibility and Safety Study. J Regen Med 4:1. doi:10.4172/2325-9620.1000119


Autologous adipose-derived stromal vascular fraction (SVF) was used to treat ten osteoarthritic knees of grades II or III (K-L scale) under an IRB-approved protocol in a feasibility and safety study. The primary objective of this study was to determine if adipose-derived SVF can be safely used for intra-articular injection of the knee. The secondary objective of this study was to evaluate the feasibility of an intra-articular injection of adipose-derived SVF for pain relief in osteoarthritic knees.

Keywords: Stem cell; Regeneration; Osteoarthritis

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