Journal of Pharmaceutics & Drug Delivery ResearchISSN: 2325-9604

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Research Article, J Vet Sci Med Diagn Vol: 3 Issue: 3

Sildenafil Efficacy on Renal Ischemia- Reperfusion Injury in Experimental Dogs

Esam Mosbah1, El- Sayed El- Shafaey1, Youssef El- Seady2, Walaa Awadin3* and Adel Zaghloul1
1Department of Surgery, Anaesthesiology and Radiology, Mansoura University, Mansoura, Egypt
2Department of Physiology, Faculty of Veterinary Medicine, Mansoura University, Mansoura, Egypt
3Department of Pathology, Faculty of Veterinary Medicine, Mansoura University, Mansoura, Egypt
Corresponding author : Dr. Walaa Awadin
Faculty of Veterinary Medicine, Mansoura University, Mansoura, Egypt
Tel: +201011610725; Fax: +20502379952
E-mail: walaafekriawadin@yahoo.com
Received: March 24, 2014 Accepted: June 09, 2014 Published: June 13, 2014
Citation: Mosbah E, El- Shafaey ES, El- Seady Y, Awadin W, Zaghloul A (2014) Sildenafil Efficacy on Renal Ischemia- Reperfusion Injury in Experimental Dogs. J Vet Sci Med Diagn 3:3. doi:10.4172/2325-9590.1000139

Abstract

 Sildenafil Efficacy on Renal Ischemia- Reperfusion Injury in Experimental Dogs

The present study reveals a catastrophic corrosive ingestion injury of upper gastrointestinal tract. A 17 year old boy intentionally ingested some corrosive acid and died due to perforation of stomach and peritonitis. The autopsy findings and toxicological analysis report confirmed that he had ingested sulphuric acid. A thorough literature review of corrosive ingestion injuries, their diagnosis and treatment allowed to show the fatality of such cases depend on the type and amount of corrosive ingested, the state of stomach whether empty or full, the promptness of treatment given and various such factors.

Keywords: Ischemia/reperfusion; Kidney; Histopathology; Apoptosis

international publisher, scitechnol, subscription journals, subscription, international, publisher, science

Track Your Manuscript

Awards Nomination
open access