Journal of Otology & RhinologyISSN: 2324-8785

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Case Report, J Otol Rhinol S Vol: 0 Issue: 1

A Case of Relapsing Polychondritis diagnosed by Biopsy of Thyroid Cartilage

Daisuke Sasaki, Junkichi Yokoyama*, Shinichi Ooba, Mitsuhisa Fujimaki, Masataka Kozima and Katsuhisa Ikeda
Department of Otorhinolaryngology, Head and Neck Surgery, Juntendo University Faculty of Medicine, Tokyo, Japan
Corresponding author : Junkichi Yokoyama, MD, PhD
Department of Otolaryngology-Head and Neck Surgery, Juntendo University Faculty of Medicine, Hongo 3-1-3, Bunkyo-ku, Tokyo 113-8431, Japan
Tel: 81-3-3813-3111; Fax: 81-3-5840-7103
Received: November 18, 2014 Accepted: March 11, 2014 Published: March 17, 2015
Citation: Sasaki D, Yokoyama J, Ooba S, Fujimaki M, Kozima M, et al. (2015) A case of Relapsing Polychondritis diagnosed by Biopsy of Thyroid Cartilage. J Otol Rhinol S1:1. doi:10.4172/2324-8785.S1-017


Relapsing polychondritis is a rare autoimmune disease characterized by recurrent inflammation and destruction of cartilage throughout the body. Prior to a definitive diagnosis, our patient suffered from a sore throat, hoarseness and persistent cough over a period of 1 month. Bone scintigraphy showed high integration of costochondral regions and thyroid cartilage. CT (computed tomography) demonstrated a hypodense area surrounded by enhancement around the thyroid cartilage. Due to respiratory dysfunction associated with general anesthesia, a diagnostic biopsy was delayed for 2 weeks. Therefore, the patient was referred to Otolaryngology Head and Neck Surgery and underwent biopsy of the thyroid cartilage under local anesthesia. The thyroid cartilage was inflamed and surrounded with aseptic abscesses. The patient was diagnosed as having relapsing polychondritis. The patient was administered a course of oral steroids. Most of the general symptoms including high fever and dysphasia disappeared. The early diagnosis based on the thyroid cartilage biopsy under local anesthesia enabled prevention of significant airway obstruction that would otherwise have been caused by thyroid cartilage inflammation. This is the first reported case of relapsing polychondritis diagnosed by biopsy of the thyroid cartilage.

Keywords: Biopsy; Early diagnosis; Local anesthesia; Relapsing polychondritis; Thyroid cartilage

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