Journal of Womens Health, Issues and Care ISSN: 2325-9795

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A Randomized Controlled Trial of the Effects of Retinyl Palmitate on CD4+ T Cell Related Cytokines, Thyroid Function and Metabolic Biomarkers in Obesity: A Study Design and Protocol

A Randomized Controlled Trial of the Effects of Retinyl Palmitate on CD4+ T Cell Related Cytokines, Thyroid Function and Metabolic Biomarkers in Obesity: A Study Design and Protocol

Obesity, as a low grade chronic inflammatory condition, is associated with immune system dysfunction and several autoimmune diseases. Recent evidence demonstrates a pathogenic role for T-helper cells in developing obesity related immune-disorders. Vitamin A and its retinoid derivates are best known for their immune-regulatory effects. However, the effect of vitamin A supplementation on immune function in obese individuals is still unknown. The aim of the present study is to investigate the possible role of vitamin A supplementation on serum T-helper cytokines and several other secondary outcomes (anthropometric and metabolic parameters and thyroid function) in healthy obese reproductive age women

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