GET THE APP

A �Theoretical� Postmortem Redistribution Factor (Ft) as a Marker of Postmortem Redistribution

Journal of Forensic Toxicology & Pharmacology.ISSN: 2325-9841

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.
noob factory rolex

A �Theoretical� Postmortem Redistribution Factor (Ft) as a Marker of Postmortem Redistribution

 A “Theoretical” Postmortem Redistribution Factor (Ft) as a Marker of Postmortem Redistribution

Postmortem redistribution (PMR) refers to the changes that can occur in drug concentrations after death. Literature supports a model describing drugs with a liver (L) to peripheral blood (P) concentration (L/P) ratio less than 5 L/kg as being prone to little or no PMR, while drugs with an L/P ratio greater than 20-30 L/kg have propensity for substantial PMR. Additionally, the concept of a post-mortem redistribution (F) factor has been recently described to express the direct relationship between post mortem peripheral blood and the corresponding antemortem whole-blood concentration. The current document expounds upon both these concepts by proposing the development of a “theoretical” postmortem redistribution factor (Ft) for a drug––based upon a drug’s characteristic L/P ratio. This model for estimating potential of PMR was produced to assist with a credible interpretation of postmortem drug concentrations.

Special Features

Full Text

View

Track Your Manuscript

Media Partners

Associations