Journal of Clinical & Experimental OncologyISSN: 2324-9110

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Atipic Axillary Mass: Follicular Dendritic Cell Sarcoma within Castleman's Disease: A Case Report and Review of Literature

Atipic axillary mass: follicular dendritic cell sarcoma within Castleman´s disease: A Case Report and Review of Literature

Follicular dendritic cell sarcoma (FDCS) is a rare neoplasm (0.4% of soft tissue sarcomas) originating from follicular dendritic cells. On the other hand, Castleman’s disease (CD) is a rare lymphoproliferative disorder first described in 1956 by Castleman et al as a benign, localized enlargement of hyperplastic lymph nodes. Castleman´s disease has been found in association with FDCS in a minority of cases, suggesting that it may represent a precursor lesion. Combination of both FDCS and unicentric CD is extremely rare.As far as we know, there are no documented cases of a follicular dendritic cell sarcoma within a hyaline-vascular Castleman´s disease localized in the axilla.There is no consensus about treatment strategy in this situation; surgical resection when possible seems to be the best option, with or without complementary radiotherapy.We present the case of a 42-year-old male with a single axillary mass identified as a FDCS in a unicentric CD in the axilla.

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