Advanced Biomedical Research and Innovation

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Bone marrow derived stem cells are efficacious in osteonecrosis of femoral head

Improved understanding of healing logistics and ortho-biologics has provided a ray of hope for treating osteonecrosis (ON) of femoral head. Purpose was to evaluate efficacy of autologous bone marrow derived mononuclear cells (MNCs) augmentation during core decompression vis–a–vis core decompression in early stages of osteonecrosis. 38 (50 hips) were randomized into Group A (MNCs with core decompression; 18/26 hips) and group B (core decompression; 20/24 hips). Bone marrow aspirated from the posterior superior iliac spine was centrifuged and the resultant MNC harvest was counted and instilled in the core decompression tracts of patients in group A.

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