Journal of Pharmaceutics & Drug Delivery ResearchISSN: 2325-9604

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Curcumin has a tendency to be rapidly metabolized and isn't easily absorbed into the blood movement

Researchers suspect that some or all painful arthritis infection may be due to free radicals inside the body. Unfastened radicals risky molecules or atoms missing an electron occur evidently within the frame, but too much reason oxidative pressure, that's connected to infection. Antioxidant meals, which include turmeric, leafy vegetables, and seafood excessive in omega three fatty acids, neutralize loose radicals. Evidence suggests cur cumin may additionally suppress the body’s reaction to tumor necrosis component (TNF), a chemical produced by using the immune gadget that reasons infection associated with rheumatoid arthritis, psoriatic arthritis, enclosing spondylitis and different arthritic conditions. Cur cumin’s position in inhibiting TNF now not yet nicely understood and research is underway. Typically non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen and naproxen, work by blocking both COX-1 and COX-2 enzymes. COX-1 enzymes influence the clotting of blood and the health of the stomach, and COX-2 enzymes influence inflammation that can lead to pain. Researchers have found that cur cumin has the chemical properties of a COX inhibitor17- and can provide modest pain relief. However, experts have not yet found a way to harness cur cumin’s COX-inhibiting properties to reliably relieve moderate or significant arthritis pain. Because cur cumin seems to have anti-inflammatory and pain-relieving effects, many people wonder why cur cumin supplements are not recommended more often. There are three primary reasons:

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