Efficacy of a Topical Lotion Containing Lactoferricin, Glycerophosphoinositol Lysine and Verbascoside for External Otitis Due to Atopic Dermatitis

Importance: Atopic dermatitis (AD) is a common skin disease in dogs with a great impact in quality of life, especially when ears are affected because of the difficult application of lotion due to the lesions localization.

Objective: This study is aimed to examine the effect of topical lotion containing lactoferricin, glycerophosphoinositol lysine and verbascoside on canine atopic dermatitis. The topical lotion must be easy to use in ears of dogs under treatment.

Methods: 21 dogs with external otitis due to atopic dermatitis were treated for 14 days and monitored from day 0 to day 14 to ascertain the effect of the treatment with different parameters such as CADESI score, lichenification, excoriation, alopecia, pruritus and cytological analysis.

Results: The lotion here prepared showed the correct density and viscosity to be used in the dogs’ ears. Thanks to the easy application, all the 21 dogs were treated for the entire period without any complain. Moreover, in all treated dogs a clear decreasing in the clinical symptoms was observed. The cytological analysis also confirms the decrease of bacteria and yeast number.

Conclusion: This study demonstrates the efficacy of a treatment based on the administration of a lotion containing the active ingredients over described in reducing clinical symptoms of canine atopic dermatitis in dogs ears.