Electrohydrodynamic Atomization (EHDA) technologies in pharmaceutical development, recent advances
Experimental pharmaceutical dosage form development and
preparation technologies have diversified over the last few decades.
In addition, the Pharma industry now has a warm willingness to
consider unconventional methods and processes for advanced and
miniaturized drug dosage form development. There are several
drivers for this ranging from the need to improve existing properties
of current systems or to develop more complex miniaturized dosage
forms by using challenging APIís; which are not possible with wellestablished
pharmaceutical technologies; once such concept which
is currently evolving as a hot prospect in the manufacturing of novel
pharmaceutical dosage forms is Electrohydrodynamic Atomization
(EHDA). This concept has been used to prepare particles, bubbles,
fibers, hollow nano-capsules as well as printed 2D and 3D structures.
There are several other crucial aspects of this technology which make it
appealing to the pharmaceutical industries (e.g. stability, formulation
and facile encapsulating ability). This talk will be broken down into
three main components. Firstly, explaining how base EHDA concepts
are ailored (from ideas) into various emerging drug dosage forms.
Secondly, examples of how recent EHDA developments are being
used to propose routes to address timely global healthcare challenges
(through novel pharmaceutical dosage form concept development and
delivery). Finally, some examples of how initiatives between industry
and academia are being advanced to maximize or mature EHDA
technologies that bring them to fruition and closer to reality (e.g., the
EPSRC-EHDA network in the UK). The talk will cover key innovation
aspects which will be beneficial to industrial and academic attendees.