Archives of Medical Biotechnology

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Inhibitory Action of Essential Oils on Quorum Sensing Activity of Pseudomonas Aeruginosa by Effecting on Pyocyanin Production

  • Background: Quorum sensing (QS) is considered an important behavior of bacterial cells that communicate with each other. Pyocyanin produced by Pseudomonas aeruginosa is one QS activity. Its synthesis can affect in the presence of essential oils.
  • Methods: Four types of essential oils of hermal seeds, black seeds, radish, and linseeds were used against the growth and pyocyanin production of P. aeruginosa.
  • Results: All four essential oils showed antibacterial activity against aeruginosa with a variable MIC value. In comparison with hermal oil, pyocyanin production was more inhibited by the other types of essential oils.
  • Conclusions: Essential oils of radish and linseeds have more antibacterial action against aeruginosa and its production of pyocyanin. Hermal oil has no effect on the QS pathway as indicated by pyocyanin production with less effect on bacterial growth.

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