Journal of Virology & Antiviral ResearchISSN: 2324-8955

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RNA Interference Technique

RNA interference is a biological proceeding in which RNA molecules inhibit gene expression or translation by offsetting attacked mRNA molecules. Double-stranded RNA-mediated interference (RNAi) is a simple and prompt method of silencing gene expression in a extent of organisms. The silencing of a gene is a outcome of deteoriation of RNA into short RNAs that activate ribonucleases to target homologous mRNA. The resulting phenotypes either are interchangeable to those of genetic null mutants or resemble an allelic series of mutants. Specific gene silencing has been shown to be related to two formaer processes, suppression in plants and quelling in fungi and has also been associated with risk management processes such as transposon silencing, protease inhibitor defence implements, gene regulation, and chromosomal reduction.

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