Symptom Patterns and Incidental Diagnosis Rates in a Multicenter Prospective UK Cohort of Patients Presenting with Suspected Renal Cancer: Challenges of Early Renal Cancer Detection

The prevalence and characteristics of symptoms in patients with suspected Renal Cell Carcinoma (RCC) will be described, and their accuracy in leading to an early diagnosis will be examined. Prospective observational cohort research across many centers. Patients presenting with a suspected newly diagnosed RCC are being recruited by eleven UK centers. Patients' reported symptoms were noted and examined. Additionally, thorough clinico-pathological and outcome data were gathered. Type and frequency of reported symptoms, incident diagnostic rate, survival without metastases, and survival with a particular cancer. The fact that related symptoms are generally uncommon and frequently linked to advanced disease limits efforts to increase public awareness of RCC-related symptoms as a strategy to increase early detection rates. The identification of circulating diagnostic biomarkers and the viability of screening methods require more focus.