Journal of Pharmaceutics & Drug Delivery Research ISSN: 2325-9604

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Targeting Spleen Tyrosine Kinase (Syk) for Treatment of Human Disease

Targeting Spleen Tyrosine Kinase (Syk) for Treatment of Human Disease

Spleen tyrosine kinase (SYK) plays a crucial role in the coordination of immune recognition receptors and orchestrates multiple downstream signaling pathways in various hematopoietic cells. In addition to its well-known function in transducing Fcγ receptor- and B cell receptor-mediated events, SYK signals downstream of a growing list of immunoreceptor pathways that modulate the innate and adaptive responses.

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