The potential role of colourless carotenoids on skin in conjugation with Glutathione: A Comprehensive review on White Tomato Extract

Carotenoids are referred to as photoprotective agents due to their antioxidant and UV absorbing properties. This activity increases in combination with other ingredients to provide synergistic effects. Apart from this, ingestion of carotenoids beyond photoprotection, has shown its additional benefit for dermal layer and thus effect on moisture and texture or elasticity of the skin, depending upon the levels of carotenoids with supplementation. Recently, colourless carotenoids i.e phytoene and phytofluene obtained from white tomato extract have gained attention due to their role in various dermatological issues. In contrast to this, glutathione has shown great potential in regulating melanogenesis. Thus, this review examines the role of these colourless carotenoids with glutathione on photoageing and depigmentation through synergistic effects and their growing relevance in dermatological care.