Biomaterials and Medical ApplicationsISSN: 2577-0268

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Zinc-doped Calcium Phosphate Coating on Titanium Surface Using Ostrich Eggshell as a Ca2+ Ions Source

Natural calcium source materials can be thermochemically processed and directly transformed into hydroxyapatite. In this work, ostrich eggshell was used as Ca2+ ions source in the preparation of zinc-calcium phosphate coatings on Ti substrates promoted by a two-step deposition method. The obtained coatings were characterized by X-ray diffraction (XRD) analysis, scanning electron microscopy with field emission gun (FEG-SEM), bioactivity using McCoy medium and toxicity with chicken embryo chorioallantoic membrane (CAM). The results showed the presence of Znbrushite and Zn-hydroxyapatite as coating phases. Bioactivity was observed in all samples showing bone-like apatite on their surface. The toxicity test showed inflammatory response between mild to moderate confirming the material’s biocompatibility. The use of ostrich eggshells was shown to be effective as a Ca2+ ions source to obtain zinc-containing hydroxyapatite coatings on Ti substrates.

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