Abdelgayoum A Abdel-Gayoum Author
Subjects of specialization
Affiliation
Serum insulin, Cortisol
Department of Clinical Laboratory Sciences, Faculty of Applied Medical Sciences, University of Hail, Hail, Saudi Arabia
Abdelgayoum A Abdel-Gayoum Department of Clinical Laboratory Sciences, Faculty of Applied Medical Sciences, University of Hail, Hail, Saudi Arabia. His publications include: 1.Farag A, Karam J, Nicasio J, McFarlane SI (2007) Prevention of Type 2 diabetes: an update. Curr.Diab.Rep 7: 200-207. 2.Vander Kooi BT, Onuma H, Oeser JK, Svitek CA, Allen SR et al. (2005) The glucose-6-phosphatase catalytic subunit gene promoter contains both positive and negative glucocorticoid response elements. Mol Endocrinol 19: 3001-3022.
Research Article Open Access
Author(s): Abdelgayoum A Abdel-Gayoum
Objectives: The present study was planned to investigate the influence of serum cortisol and age differences on insulin resistance and the associated lipid disturbances in euthyroid adults.
Methods: Hyperglycemic, hyperinsulinemic patients were recruited, and classified according to their insulin resistance (HOMA-IR) into: Normal insulin sensitivity (NIS), moderate- (MIR), high insulin resistance (HIR) with HOMA-IR<4, 4.1 to 6, and >6, respectively. The patients were also classified into three age-range groups: young age (YA), middle age (MA), Old age (OA); with age ranges <30, 31-40 and >40 yrs., respectively. Fasting serum was used for analysis.
Results: The serum cortisol of HIR wa... view moreĀ»