Adebowale Adeniran Author
Subjects of specialization
Affiliation
cancer, cancer oncology, Carcinogenesis
Department of Pathology, Yale University School of Medicine, New Haven, Connecticut, USA
Dr. Adebowale Adeniran is working as scientist and professor at Department of Pathology, Yale University School of Medicine, New Haven, Connecticut, USA. The author has specalization in cancer, cancer oncology, chemotherapy, Carcinogenesis, Chemotherapy
Case Report Open Access
Author(s): Serhan Unlu, Michael J Grant, Scott Gettinger, Adebowale Adeniran, and Harriet M Kluger
Immune checkpoint inhibitors are currently employed for treatment of various malignancies, including advanced melanoma and non-small cell lung cancer. As more patients are treated with checkpoint inhibitors, situations will arise in which early-stage disease may be subjected, intentionally or unintentionally, to these agents. This is especially relevant for patients presenting with multiple primary malignant tumors (MPMTs). Here we report the case of a patient presenting synchronously with metastatic melanoma to multiple regional lymph nodes and stage I lung adenocarcinoma with high programmed-death ligand 1 (PD-L1) expression. Given the high-risk nature of his melanoma, he was treated with nivolumab monotherapy, and had a durable response of both malignancies to a PD-1 inhibitor. He re... view moreĀ»