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Aditya Aggarwal Author
Subjects of specialization
Affiliation
Applied Microbiology, Applied Microscopy, Applied Mycology, Applied Physiology, Biomedical Research
Post Graduate Institute of Medical Education & Research, India
Biography
Aditya Aggarwal currently is a Professor and Head unit II Department of Orthopaedic Surgery, Post graduate in Institute of medical education and research Chandigarh India. He has vast experience of more than 30 years in his field as researcher, teacher and surgeon. He has published more than 80 publications in journals of repute with more than 700 citations and H index of 15.
Publications
Short Communication Open Access
Autologous bone marrow derived mesenchymal stem cells as a novel therapy for articular cartilage defects in osteoarthritis knee
Author(s): Aditya Aggarwal
Osteoarthritis of the knee is a leading cause of morbidity. No effective therapy is available today that alters the pathobiology course of osteoarthritis. Aim was to study the safety and efficacy of mesenchymal stem cells (MSCs) in knee osteoarthritis. 12 patients with Ahlbacks’ grade one or two bilateral osteoarthritis knees were enrolled. 8 to10 ml of bone marrow was aspirated under strict aseptic precautions from iliac spine. After stem cell culture and expansion for four to six weeks, cells which were found adherent to the culturing flask were removed with 0.05% trypsin-EDTA solution and characterized using antibodies. Cells positive for CD 90 and CD 105 and negative for CD 45 and CD 34 were the mesenchymal stem cells. These were then sub-cultured. MSC suspension in 10xPBS was... view more»
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