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Aggarwal Aditya Author
Subjects of specialization
Affiliation
Arthritic conditions, Bursa inflammation (Bursitis), Fibrositis (Fibromyalgia syndrome), Fractures, Kyphosis
Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran
Biography
Reza Moghadasali has completed my PhD at the age of 35 years from Kharazmi University, Iran. I am the director/assistant professor of Royan Institute, Iran. I have over 22 publications that have been cited over 500 times, and my publication H-index is 10 and has been serving as an editorial board member of reputed Journals
Publications
Short Communication Open Access
Autologous bone marrow derived mesenchymal stem cells as a novel therapy for articular cartilage defects in osteoarthritis knee
Author(s): Aggarwal Aditya
Osteoarthritis of the knee is a leading cause of morbidity. No effective therapy is available today that alters the pathobiologic course of osteoarthritis. Aim was to study the safety and efficacy of mesenchymal stem cells (MSCs) in knee osteoarthritis. 12 patients with Ahlbacks’ grade 1 or 2 bilateral osteoarthritis knees were enrolled. 8-10 ml of bone marrow was aspirated under strict aseptic precautions from iliac spine. After stem cell culture and expansion for 4-6 weeks, cells which were found adherent to the culturing flask were removed with 0.05% trypsin-EDTA solution and characterized using antibodies. Cells positive for CD 90 and CD 105 and negative for CD 45 and CD 34 were the mesenchymal stem cells. These were then subcultured. MSC suspension in 10xPBS was injected direc... view more»
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