Ahmed Elewa Author

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Dilemma of Hepatic Ischemia Reperfusion Injury after Liver Transplantation

Author(s):

Mohamed Ismail Seleem, Ahmed Elewa

Liver transplantation, whether from a deceased or living donor (LDLT), is still a definite line of treatment for decompensated cirrhosis, early stage of hepatocellular carcinoma, and acute liver failure. Organs from living donors offer many potential advantages over organs from deceased donors; the most important is the optimization of the timing of transplantation. Also preservation time is minimal, so there is significantly less ischemic damage. Time-zero biopsies sampled after graft revascularization predicts adverse clinical outcomes after liver transplantation. It is well known that severe Ischemia/reperfusion injury (IRI) signals the likely need for early retransplantation. This fact emphasizes the value of the time –zero biopsy sampled immediate... view more»

DOI: 10.4172/2325-9612.1000159

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