Clinical Oncology: Case Reports

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Akesh Thomas Author

thomasa16@etsu.edu

Subjects of specialization
cancer, cancer oncology, Carcinogenesis, Cancer Diagnostics, Diagnosis

Affiliation
Department of Internal Medicine, East Tennessee State University, Johnson City, USA

Biography

Dr. Akesh Thomas is working as scientist and professor at Department of Internal Medicine, East Tennessee State University, Johnson City, USA. The author has specalization in cancer, cancer oncology, chemotherapy, Carcinogenesis, Chemotherapy, Diagnosis Cancer Diagnostics, Early Detection of Lung Cancer Lung Cancer Prevention Smoking Cessation Methods Health Care Disparities in Lung Cancer Prevention and Screening Health Equity

Publications

Case Report Subscription

Pembrolizumab Associated Pericardial Effusion In A Patient With Advanced Esophageal Cancer

Author(s):

Akesh Thomas, Emmitt Lee Turner, Lawrence Sevilla Parwan and Sajin M Karakattu

Pembrolizumab is an Immune Checkpoint Inhibitor (ICI) that exerts anti-tumor activity by inhibiting the interaction of programmed cell death protein 1 with its ligand (PD-L1) on activated lymphocytes.Immune Related adverse effects are a major concern for the use of ICI. We are reporting the case of a 64 year old white male with advanced esophageal adenocarcinoma who presented with moderate pericardial effusion after receiving treatment with pembrolizumab. The patient was treated with systemic steroids which improved his condition. Clinicians should consider the possibility of Immure related adverse effects in patients receiving immunotherapy with a wide array of presentations.

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