Clinical Oncology: Case Reports

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Amanda Parkes Author

Subjects of specialization
cancer, cancer oncology, Carcinogenesis

Affiliation
The University of Texas MD Anderson Cancer Center, Division of Cancer Medicine, U.S.A; University of Wisconsin Carbone Cancer Center, U.S.A

Biography

Dr. Amanda Parkes is a faculty member in the Division of Hematology, Medical Oncology and Palliative Care within the Department of Medicine. During her fellowship she received the Jesse H. Jones Fellowship in Cancer Education, an Endowed fellowship award presented to a clinical fellow at the University of Texas ? MD Anderson Cancer Center demonstrating potential for excellence in and unique contribution to cancer education.


Publications

Case Report Open Access

Unusual Sanctuary Site (Central Nervous System) Metastases in Gastrointestinal Stromal Tumor Patients

Author(s):

Amanda Parkes*, Filip Janku, Shubham Pant and Neeta Somaiah (USA)

Gastrointestinal Stromal Tumor (GIST) metastases occur in 18%47% of patients and most commonly involve the liver and peritoneum.  Central Nervous System (CNS) and other sanctuary site metastases are rare, with only limited single patient case reports available in the literature. Given the availability of multiple effective treatments and longer life expectancy in patients with metastatic GIST, there is an increased likelihood of metastases to sanctuary sites including the CNS. We sought to characterize three GIST patients who developed these rare sanctuary site metastases between 2017-2018 during their course of therapy and compare their clinical features and molecular profiles, to add to current knowledge and highlight the need for clinicians to consider sanctuary site metastases,... view moreĀ»

Abstract HTML PDF



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