Andrew VDoodnauth Author
Subjects of specialization
Affiliation
cancer, cancer oncology, Carcinogenesis
Department of Internal Medicine, State University of New York, Downstate Health Sciences University, Brooklyn, New York, United States
Dr. Andrew VDoodnauth is working as scientist and professor at Department of Internal Medicine, State University of New York, Downstate Health Sciences University, Brooklyn, New York, United States. The author has specalization in cancer, cancer oncology, chemotherapy, Carcinogenesis, Chemotherapy
Case Report Subscription
Author(s): Andrew V Doodnauth, Miriam M. Klar, Zohra Malik, Krunal H Patel, Daniela Tello, Safi Afzal and Samy I McFarlane
Immune checkpoint inhibitors have opened a new era in the treatment of advanced malignancies, resulting in increased use and remarkable clinical responses. However, there has been an increase in the incidence of immune-related adverse events as a result of the immunologic effects of these therapies. Kidney immune-related adverse events incidence is reported as low at 2% to 5%1. Renal toxicity commonly described includes acute interstitial nephritis, minimal change disease, immune complex glomerulonephritis2. Renal tubular acidosis (RTA) has occasionally been reported but is uncommon. We report a patient with a known history of metastatic melanoma undergoing treatment with Ipilimumab + Nivolumab who developed an RTA and was successfully treated with stress dose ster... view moreĀ»