Anish B Author
Subjects of specialization
Affiliation
Nanotechnology, Nanoparticles, Cancer, Cell Culture, Cancer Biology
Stephenson Cancer Centre, University of Oklahoma Health Sciences Centre, Oklahoma City, United States
Chemo-biologic combinatorial drug delivery using folate receptor-targeted dendrimer nanoparticles for lung cancer treatment is one of the research works of Anish Babu. Anish Babu is from Stephenson Cancer Centre, University of Oklahoma Health Sciences Centre, Oklahoma City, United States.
Research Article Subscription
Author(s): Amsaveni G, Sakthivel M, Kathiravan K, Anish B and Murugesan R
Objective: Chitosan nanoparticles (CS-NP) can imbibe water insoluble anticancer agents into its hydrophobic multicores. In the present study, chitosan nanoparticles, a nanoscale drug carrier system is investigated for its potential as a drug delivery system for porphyrin based photodynamic therapy. Methods: Zinc meso tetra phenyl porphyrin (ZnmTPP) encapsulated CS-NP was prepared by ionic gelation method. The synthesized nanoparticles were characterized using dynamic light scattering studies, zeta potential analysis and AFM analysis. Results: Freshly prepared chitosan nanoparticles had an average hydrodynamic diameter of 175 nm and are nearly spherical in shape as per light scattering measurements and atomic force imaging respectively. As nanoscale drug carriers, (ZnmTPP) encapsulated c... view moreĀ»